Recorded lectures and videos for all subjects within the Organic II Curriculum by David Tompkins.
1. Resonance
2. Acid-Base: An Organic Perspective
3. Acid-Base: Application
4. 1H NMR: Chemical Shift
5. 1H NMR: Topicity & Equivalence
6. 1H NMR: Chemical Equivalence
7. 1H NMR: Integration
8. 1H NMR: Splitting
9. 1H NMR: Solving Spectra: Techniques
10. 1H NMR: Structural Elucidation I
11. 1H NMR: Structural Elucidation II
12. 1H NMR: Structural Elucidation III
13. 1H NMR: Structural Elucidation IV
14. Alkyne Reactions: Intro
15. Alkynes: Addition of HX
16. Alkynes: Bridge Intermediates
17. Alkynes: Mercury-Catalyzed Hydration
18. Alkynes: Hydroboration-Oxidation
19. Alkynes: Reduction
20. Alkynes: Acetylide Ions
21. Alkynes: Synthesis
22. Dienes and Delocalization
23. Conjugated Dienes: MO’s, 1,2/1,4 Additions, and K vs.T
24. Diels-Alder
25. Aromaticity
26. Aromatic Compounds
27. Frost Diagrams
28. Aromaticity: Concepts
29. EAS: Intro
30. EAS: Halogenation
31. EAS: Friedel-Crafts Alkylation
32. EAS: Friedel-Crafts Acylation
33. EAS: Nitration and Sulfonation
34. EAS: Directing Groups & EDG's
35. EAS: EWG's as Deactivators
36. EAS: Activators and Deactivators
37. EAS: Regioselectivity
38. NBS: Allylic & Benzylic Bromination & Synthesis
39. Alkyl, Allyl, Vinyl, Aryl, and Benzyl Reactivities
40. Allylic & Benzylic Reactivity towards SN1
41. Allylic, Benzylic, and Phenolic Acidity
42. Allylic & Benzylic Carbanions
43. Allylic & Benzylic Reactivity towards SN2
44. Aryl & Vinyl Halides: Inert Towards SN1/SN2
45. Nucleophilic Aromatic Substitution: Addition-Elimination
46. Nucleophilic Aromatic Substitution: Elimination-Addition via Benzyne
47. Substitution Mechanisms: Aryl, Vinyl, Alkyl, Allylic & Benzylic Halides
48. Alcohol Oxidation
49. Organometallics I
50. Organometallics II
51. Intro to Carbonyls
52. Aldehydes & Ketones: Reactivity
53. Aldehydes & Ketones: Irreversible Additions
54. Aldehydes & Ketones: Reduction
55. Aldehydes & Ketones: Cyanohydrin Formation & Reversal
56. Aldehydes & Ketones: Hydration
57. Carbonyl Reactivity
58. Aldehydes & Ketones: Addition of Oxygen Nucleophiles
59. Aldehydes & Ketones: Acetals & Ketals
60. Aldehydes & Ketones: Protecting Groups
61. Aldehydes & Ketones: Synthesis
62. Aldehydes & Ketones: Imines & Enamines
63. Condensation Reactions of Aldehydes & Ketones
64. Aldehydes & Ketones: Wittig Reaction
65. Intramolecular Wittig Olefination
66. Alpha-Beta Unsaturated Ketones: 1,2 (Direct) vs. 1,4 (Conjugate) Addition
67. Carboxylic Acid Derivatives 1: Intro to Nucleophilic Acyl Substitution
68. Carboxylic Acid Derivatives 2: Relative Reactivity
69. Trends in Carbonyl Reactivity, α-H acidity, and Carbonyl O Basicity
70. Trends in Carbonyl Reactivity
71. Carboxylic Acid Derivatives 3: Acidity and Hydrolysis
72. Acetal Formation & Fischer Esterification
73. Carboxylic Acid Derivatives 4: Synthesis and Stoichiometry
74. Carboxylic Acid Derivatives 5: Irreversible Additions and Reductions
75. Acid Chlorides & Organocuprates (Gilman Reagents)
76. Carbonyl Reactivity: Reduction with Hydrides
77. Synthesis via Carbonyls
78. Enolates 1: Intro, Tautomerization, and Halogenation
79. Enolates 2: Alkylation
80. Enolates 3: Named Reactions
81. Enolates 4: Aldol Reactions
82. Aldol Reactions: Crossed, Intramolecular, and Retro
83. Enolates 5: Claisen Condensations
84. Claisen and Dieckmann Condensations I
85. Claisen and Dieckmann Condensations II
86. Enolates 6: Michael Addition and Robinson Annulation
87. Michael, Robinson, and Retrosynthesis
88. Enolate Retrosynthesis
89. Decarboxylation and Synthesis
90. Alpha-Carbon Nucleophiles
91. Basicity of Nitrogen-Containing Compounds
92. Amine Basicity
93. Amine Synthesis via SN2
94. Reductive Amination
95. Reduction of Amides & Nitriles
96. Hoffman Elimination
97. Curtius Rearrangement
98. Amine Synthesis
99. Amino Acids: pI and Chirality
100. Amino Acid Synthesis
101. Carbohydrates: Acyclic Stereochemistry
102. Carbohydrates: Epimerization
103. Carbohydrates: Tautomerization
104. Carbohydrates: D-Glucose
105. Carbohydrates: Cyclization
106. Carbohydrates: Cyclic D vs. L
107. Carbohydrates: The Anomeric Carbon
108. Carbohydrates: Mutarotation
109. Carbohydrates: Glycosides
110. Carbohydrates: Anomeric Carbon Reactivity
111. Carbohydrates: Reducing Sugars
112. Carbohydrates: Glycosidic Linkages
113. Carbohydrates: Review
114. Themes 1: Carbonyl Stability
115. Themes 2: Resonance Predicts Reactivity
116. Themes 3: Acid-Base: Kinetics vs. Thermodynamics
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